TREASURE CHEST 1

All treasure chests require the lock pick to open. Once you have acquired it, fast travel to the Temple District Base Camp on the west side of lower Paititi. Head southeast, past one flight of stone steps, then down a second flight of steps into the courtyard with monolith #5. The chest is inside the building southwest of the monolith, where you met Pisco the Dead during the Dice with the Dead Side Mission. Use the lock pick to open the chest and obtain an Artifact, an Airplane (Myth, Magic & Monsters). (Click images for more and larger screenshots.)

Check the level map if necessary. Treasure chests are numbered in orange. Monoliths are aquamarine.

TREASURE CHEST 3

Once you've returned from the Cenote, obtained the Serpent Guard disguise, and are able to explore upper Paititi, you'll find this treasure chest there. If you missed it the first time, fast travel to the Upper City Main Gate Base Camp. Climb the stairs and continue through the upper city marketplace along the right (east) side. Before you reach the farthest corner of this area, you'll see stairs leading down into a dimly lit room with a burning torch. The treasure chest is here. It's also one of the places you may find the traveling merchant, Moraekah, who sells the lock pick. Use this tool to open the chest. Inside is an Artifact, Ear Spools (Day in the Life of a Paititian). (Click screenshots to enlarge.)

Again, check the walkthrough and map if you need help getting oriented.

RELIC 2 - Chuspas (Day in the Life of the Inca)

Just south of the Paititi Market Base Camp is a large white building with blue dye dripping from its windows. Climb the stairs and enter through the open doorway to find the relic. (Click screenshot to enlarge.)

RELIC 4 - Whistle (Day in the Life of a Paititian)

The box containing this relic is just a few steps southwest of the Temple District Base Camp. It's sitting on the right side of the wide steps outside the temple entrance. (Click screenshot to enlarge.)

RELIC 6 - Patolli Mat (Day in the Life of a Paititian)

This relic is in the same building as treasure chest #1 (above). Start at the Temple District Base Camp, head south then east to monolith #5. The chest is inside the building southwest of the monolith. (Click screenshots to enlarge.)

RELIC 8 - Ceremonial Torch (Secrets and Lies)

This relic is on a high ledge at the south end of the city. From the Village Caves Base Camp, exit the cave, climb the manmade stone ledges with the irrigation channels on the left, then climb the long staircase leading up to the west. (screenshots) At the top of these stairs, just before the cave entrance, scale the climbing wall on the left to reach the ledge with mural #6. Climb the wall to the left of the mural, continue climbing around to the left, jump over to the next climbable section, then rappel down onto the ledge with the relic. (screenshots) From there, you can continue left to the Temple of the Sun Challenge Tomb or drop back down to the stairs on the right. (Click screenshot to enlarge.)

RELIC 10 - Chaki Taklla (Day in the Life of the Inca)

This relic is on the east side of the river in the same general area as Unuratu's Home and Skull Cave. If you're coming from the west, take the small wooden bridge across the river. Then turn left and go up two flights of steps to find the relic (and document #10) in a small alcove near the rope ladder leading up to Unuratu's Home.

Or, head down the steps/zip line from Unuratu's Home to find the document. (screenshots) Referencing the map, the relic is just to the left (west) of Skull Cave and the middle of the zip line. (Click screenshots for more and larger images.)

RELIC 12 - Plastic Penguin (Myth, Magic & Monsters)

This relic is just down the hill from relic #11 and monolith #3 (above). If you ride the zip line down, you'll find the relic in a box at the base of the little wooden shack. If you're coming from below, it's on the left behind the shack. (Click image for screenshots showing the relic from above and below.)

RELIC 14 - Ch'arki and Chuños (Day in the Life of a Paititian)

This relic is on the east side of the river, just north of the bridge leading to the upper city. The nearest base camps are Unuratu's Home and, later, Skull Cave. From monolith #4, head down the steps to the south and you'll come to a hut with a rope barrier blocking the entrance. Once you've purchased the REINFORCED KNIFE upgrade from one of the merchants in the MARKET, you can cut down this barrier to find the relic and some other supplies inside. Survival cache #15 is buried near the hut. (Click image for more and larger screenshots.)

RELIC 16 - Macuahuitl (Cult of Kukulkan)

This relic is inside the temple on the west side of the city, on the way to the Belly and Head of the Serpent. If you missed it, fast travel to the Temple District Base Camp and re-enter the temple. Follow the tunnel to the room with the relic. Then return to the camp the way you came. (Click image for more and larger screenshots.)

RELIC 18 - Copper Mace (The Resistance)

This relic is inside Skull Cave, which is only accessible after returning to Paititi from the Cenote. Either fast travel to the Skull Cave Base Camp, assuming you've been there before, or look for the Heron-and-Eclipse icon marking the cave entrance on the in-game map south/southeast of Unuratu's Home. The relic is inside the small, stone-walled room in the middle of the cave. (Click screenshot to enlarge.)

RELIC 20 - Tlaloc Vase (Pantheon of Gods)

This relic is also in the upper city, which is only accessible after completing the Cenote. If you missed it the first time, fast travel to the Upper city Main Gate Base Camp and follow the upper walkway around to the south end to find the relic sitting on a table with some other ceremonial offerings. (Click image for more and larger screenshots.)

RELIC 22 - Bloodletter (Pantheon of Gods)

The next three relics, #22, #23, and #24 are inside the Temple of Kukulkan. If you missed them on your way to rescue Unuratu from prison, fast travel to the Temple of Kukulkan Base Camp and re-enter the temple through the doorway to the west. The first of the three relics is sitting on the floor near the ornate altar in the middle of the room. (Click image for more and larger screenshots.)

Note that the Temple of Kukulkan Base Camp does not appear until you've completed this area and reached the Porvenir Oil Fields. You can also re-enter the temple through the doorway at the top of the stairs north of the Upper City Main Gate Base Camp.

RELIC 24 - Mask of Tezcatlipoca (Pantheon of Gods)

This relic is also inside the Temple of Kukulkan in upper Paititi (directions under relic #22, above). Once you reach the temple, head for the corridor that runs along the north wall behind the altar. You'll find this relic and document #32 about halfway along, opposite the shallow pit with burning coals. (Click image for more and larger screenshots.)

RELIC 26 - Map of Search Areas (Trinity)

This relic is in the guard room near Unuratu's prison cell in the gorge east of the city. Fast travel to the Temple of Kukulkan Base Camp, accessible once you've finished the Porvenir Oil Fields. Cross the first bridge to the island. Then climb the stairs and cross the second bridge to the east side of the gorge. The relic is in the guard room at the end, along with documents #35 and #36 and archivist map #6. (Click image for more and larger screenshots.)

RELIC 28 - Arrow (Inside Out)

This relic is in the Crypt of Ollanta, The Potter, west of the city in the same area as the Path of Battle Challenge Tomb. (See relic #27, above.) From the Wild Jungle Base Camp, follow the stream south to the crypt entrance, which is at the top of the waterfall. (The crypt walkthrough explains how to climb up.) Follow the dark passageway into the crypt. The relic is sitting on the ground just beyond the concealed spike pit. (Click image for more and larger screenshots.)