Two assassins come out as soon as you enter the FIRST (NORTH) ROOM, one from the doorway ahead and a little to the left, one on the far left.
If you want all the pickups run to the left and quickly grab the small medipack sitting on the low block.
If you don't, one of the assassins will steal it and you won't see it again.
Then backflip away a few times and take out the assassins.
- OR -
If you don't care about that item, instead, when you first enter the room, run to the right..
...head for the (southwest) corner and use the stone blocks there to climb onto the ledge above to avoid the assassins' blades.
You can then shoot them from above. One will probably draw a gun if you engage him for a while. So you might want to switch to a more powerful weapon at this point.
The other may lurk under the ledge. If so, change position or hang from the edge and pull up in order to draw him out.
The shooter drops his UZI (or Uzi clips if you already have the guns) when he dies.
Go through the small, connecting room in the middle of the south wall, lower level. This leads into the MIDDLE ROOM.
When you approach the shotgun shells...
...a third assassin emerges from behind the block to the right. Deal with him as you did the others.
Pick up the ammo and then enter the small room to ahead on the right (southwest)...
...to get a large medipack.
Vault back up into the doorway, turn around, and grab the ledge above. Pull up into the small room above and move through to the other side.
From the doorway, you can get a clear shot at the fourth assassin lurking below.
If you use pistols to conserve ammo, he may flee through the doorway into the MIDDLE ROOM.
If that happens, just turn around, return through the small room to the other doorway, and shoot him from there.
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