Slide into the sewers and kill the rat (1) just ahead. If you use the K2 Impactor to shock it, this will count toward the "Electrocuties" achievement/trophy, for defeating two different non-human enemies by tasing them. (The other will be a bat in the TOMB OF THE ANCIENTS level. I'll remind you.)
NOTE: This particular rat doesn't seem very aggressive, but remastered rats can poison Lara with their bite, causing your health bar to turn green and begin to drain. (screenshot) Use an antidote from the Health section of your inventory (assuming you bought some from the WILLOWTREE HERBALIST) or use a large health pack for a full recovery. Smaller health items will restore Lara's health, but not cure the poison.
Follow the tunnel to a shallow pool. Pick up the chocolate bar (1) on the ground to the left. (I guess fugitives can't be too particular about where they get their snacks.) Climb the stairs just ahead...
...and get a large health pack (2). The door here doesn't open so return downstairs.
Hop down into the shallow water and proceed through the sewer pipe, shooting another rat (2) along the way.
Enter the narrow passage on the left.
Wade into the water and swim forward to a small, flooded room where several tunnels converge.
There are no other exits, so climb the ladder. (Maybe quick-save as you climb.)
At the top is a SMALL ROOM WITH A VALVE, where Lara is immediately attacked by an aggressive rat (3). Shoot it and use an antidote if necessary.
Lara isn't strong enough to turn the valve yet. So, for now, follow the narrow hallway.
Pick up a Vector clip (3) just below the pipe venting steam. Then continue through two open doors...
...to another wider tunnel. Turn right and proceed to a hub where several wide tunnels meet.
Avoid the deep hole in the center of the room. You can walk around the sloping rim, but if Lara falls into the hole, she'll die. Notice the water falling from above. You'll need to do something about that.
First, go around to the right and shoot the rat (4) in the tunnel ahead, so you don't have to deal with it later. (Again, use the K2 taser for at least one of the rats if you want the "Electrocuties" achievement/trophy later in the game.)
The valve-monitoring station, on this side of the hub room, has various lights and dials which can't be manipulated. It displays the state of the 6 valves you'll be using soon.
Move around to the far side of the hole and climb the vertical pipe to the catwalk above.
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