City of the Serpent – Boss Fight – Dominguez/Kukulkan
Without Fear Arrows (part 4)

Use the same basic tactics for the next round. Back away shooting, dodge if necessary, and ignore the minor enemies unless they get in your way. Continue to heal and use Focus/Endurance herbs as needed.

Activating Focus (by using the herbs and holding Aim to slow time) should also allow you to land more headshots even as you're backing away from Dominguez. If you run out of rifle ammo, you can switch weapons, but hopefully it won't come to that.

After a bit more of this, the golden energy sphere surrounds him again.

Rush in and press the button indicated for a fourth melee attack.

Lara knifes Dominguez in the back. He elbows her in the face, throwing her off balance and stunning her momentarily.

As you regain control following the cutscene, Dominguez slashes out with his blade. You can try to dodge...

...but the blast of fire will probably still knock Lara down.

Now that he's near death, Dominguez begins to aggressively teleport. The snake of glowing energy shows where he'll turn up next...

...usually right next to Lara.

If things get rough, run away again. Dominguez will run or teleport after you, but this should give you a few moments to heal and use other herbs.

Turn and hit him with whatever you have left. Rifle ammo is great, but if all you have is shotgun or pistol rounds, grenades, or even arrows, just go for it.

After a few more hits...

...the golden bubble surrounds Dominguez once more. Run toward him...

...and press Melee to stab him a fifth and last time.

And it's done. Lara gently, almost reverently, eases the dying Dominguez to the ground. The ending then unfolds in a series of cutscenes.